Parkinson’s Gene Therapy Safe, Appears to Ease Motor Symptoms

Treatment with Askbio‘s gene therapy candidate AB-1005 is safe and appears to ease motor symptoms in people with either a recent or a long-standing diagnosis of Parkinson’s disease.

That’s according to the full results of a small Phase 1 clinical trial conducted by the gene therapy’s developer at three sites in the U.S.

Based on the positive data from that Phase 1 study, Askbio is now running a Phase 2 clinical trial called REGENERATE-PD (NCT06285643). That trial, which is enrolling an estimated 87 adults with moderate Parkinson’s, aims to test AB-1005 against a sham procedure.